Menene paclitaxel, paclitaxel don dakatarwar allura da kuma paclitaxel mai ɗaure albumin? Menene babban amfani? Za mu bayyana su a taƙaice a cikin wannan labarin.
A na halitta na biyu metabolite ware da kuma tsarkake daga haushi, rassan da ganye na gymnospermous taxus chinensis na iya inganta microtubule polymerization da kuma daidaita da polymerized microtubules.Cells fallasa su paclitaxel zai tara babban adadin microtubules a cikin sel.Tarin wadannan microtubules tsoma baki. tare da ayyuka daban-daban na sel, musamman dakatar da rabon tantanin halitta a matakin mitotic, kuma yana toshe rabon tantanin halitta na al'ada.
Yana da sakamako mai kyau na anti-tumor kuma ana amfani dashi don magance ciwon nono mai ci gaba, ciwon huhu, ciwon daji, ciwon kai da wuyansa, ciwon daji mai laushi da kuma ciwon daji na hanji.
Paclitaxel (Taxol) API ne na anticancer (Active Pharmaceutical Ingredient), wanda mutane ba za su iya amfani da su kai tsaye ba. Yana buƙatar a ba da shi ga kamfanoni na ƙasa ko masana'antar harhada magunguna don zama ɗaya daga cikin API na gamayya magunguna.
A halin yanzu, mafi yawan amfani da paclitaxel shine alluran rigakafin ciwon daji da na'urorin likitanci (ciki har da stent da balloons). Ci gaba da ingantawa. Yi imani da cewa nan gaba kadan, zai kasance mafi aminci kuma mafi dacewa ga maganin likitoci da marasa lafiya, kuma za a sami karin nau'in magungunan ciwon daji masu dauke da paclitaxel tare da tasirin maganin ciwon daji.
Paclitaxel don Dakatar da Injectable:
Allura mai dauke da paclitaxel API.
Paclitaxel don allura kuma ya haɗa da alluran polyoxyethylene castor oil paclitaxel allura, Liposome paclitaxel allura; Albumin bound paclitaxel allura; Micellar paclitaxel da sauran nau'ikan nau'ikan nau'ikan nau'ikan nau'ikan nau'ikan nau'ikan nau'ikan nau'ikan nau'ikan nau'ikan nau'ikan nau'ikan nau'ikan nau'ikan nau'ikan nau'ikan nau'ikan allura.
Ana amfani da shi sosai wajen magance cutar kansar nono, da ciwon huhu, ciwon huhu da sauran cututtuka, kuma yana daya daga cikin magungunan da ake amfani da su wajen magance cutar kansa a halin yanzu.
Albumin Bound Paclitaxel:
Albumin bound paclitaxel allura shiri ne mai haɗa paclitaxel da albumin. Yana da na paclitaxel don allura kuma yana ɗaya daga cikin allurar paclitaxel da aka fi amfani da ita tare da babban aminci.
Albumin paclitaxel, na farko da ya fara shiga idanun mutane shine allurar ABRAXANE (ABRAXANE For Injectable Suspension paclitaxel protein-bound barbashi don dakatarwar allurar, albumin-daure) FDA ta amince da ita a cikin 2005, wacce ake amfani da ita don magance cutar kansar nono. sake rushewa yana da kusan 130 nm, kuma ba ya ƙunshi abubuwa masu guba masu guba. Tasirin aminci da tasirin warkewa ya fi girma fiye da na shirye-shiryen irin wannan, kuma yana da mashahuri sosai. Har ila yau yana daya daga cikin manyan dalilan bincike da kwaikwayo. na manyan kamfanonin harhada magunguna nan gaba.
Ya fi dacewa da maganin ciwon daji na nono wanda ya gaza a hadewar chemotherapy ko ciwon nono wanda ke komawa cikin watanni 6 bayan adjuvant chemotherapy.
Yunnan Hande Bio-Tech ta himmatu wajen gudanar da bincike da haɓakawa da samar da supaclitaxel,docetaxel,10-DAB Semi-synthetic paclitaxel,kumacabazitaxel,kuma yana da cikakken bincike na bayanai game da ƙazanta daban-daban da ke cikin paclitaxel. Bugu da ƙari, Hande yana ba da sabis na canja wurin fasaha da suka shafi paclitaxel: magungunan gargajiya na paclitaxel; Album bound paclitaxel injections da dai sauransu, barka da zuwa tuntube mu don tambaya!(Whatsapp/Wechat:+86) 18187887160)
Lokacin aikawa: Fabrairu-09-2023