Paclitaxel, Maganin rigakafin ciwon daji na halitta daga Taxus chinensis

Paclitaxel wani sinadari ne da aka fitar daga yew, wanda zai iya hana cutar kansa yadda ya kamata, kuma maganin tauraruwar da ake amfani da shi ne a duniya. Binciken asibiti, an ƙaddamar da allurar paclitaxel ta farko “Taxol” a cikin 1992. Har zuwa yanzu,paclitaxelyana daya daga cikin sanannun magungunan maganin ciwon daji tare da inganci mai kyau.Yana da halaye na ingantaccen inganci, ƙarancin guba da kuma bakan bakan.Yana da tasirin warkewa na zahiri akan ciwon daji na ovarian, ciwon nono, m Melanoma, ciwon huhu, kansar prostate, kwakwalwa. ciwon daji da ciwon daji.

Sakamakon gwaje-gwajen likita ya nuna cewa, a halin yanzu, samunpaclitaxel APIsyafi dogara ne akan hakar tsire-tsire na Taxus chinensis da Semisynthesis sinadarai.Masu binciken kimiyya suna tattara rassan da aka noma artificially da ganyen Taxus chinensis chinensis, amfani da hakar sauran ƙarfi, tsantsa mai tsauri, cirewar ruwa mai ƙarfi, rabuwar membrane, rabuwar chromatographic da sauran hanyoyin rabuwa da hakar don cire precursors kama da tsarin paclitaxel, kamar bacatine III,10 deacetyl bacatine III, da dai sauransu, sa'an nan samun likita paclitaxel girma magunguna ta hanyar sinadaran gyara na taro samar da hanyoyin.

A cewar kididdigar masana kimiyya, masu ciwon daji suna buƙatar cinye fiye da 2 grams napaclitaxela cikin hanya guda na magani.Wadannan alamun paclitaxel suna buƙatar fitar da su daga haushin bishiyoyin Taxus chinensis na daji 4-8 waɗanda suka girma fiye da shekaru 50. A gefe guda, Taxus chinensis da paclitaxel suna da yawa, kuma akan a daya hannun kuma, akwai wata babbar bukatar likita, wanda ke haifar da tsadar kayan albarkatun Taxus chinensis duk shekara, kuma wadatar ta ragu da buƙata.

Bayani: Yiwuwar inganci da aikace-aikacen da aka ambata a cikin wannan labarin duk sun fito ne daga wallafe-wallafen jama'a.

Extended karatu: Yunnan Hande Bio-tech ne yafi tsunduma a cikin hakar da kuma bunkasa haraji. Its core kayayyakin su ne na halitta Paclitaxel,10-DAB Semisynthesis Paclitaxel,10-DABIII,docetaxel,cabataxel,da sauransu.Idan kana bukatar ka sani game da paclitaxel tushen. albarkatun kasa, da fatan za a iya tuntuɓar mu a.