Ta yaya ake yin paclitaxel Semi-synthetic?

Paclitaxel, maganin cutar kansa na halitta, ana fitar da shi ne daga Taxus chinensis.An yi amfani da shi sosai wajen magance cutar kansar nono, da ciwon daji na ovarian, da wasu kansa da wuyansa da ciwon huhu a asibiti.Paclitaxel ya kasu kashi na halitta.paclitaxelkumaSemi-synthetic paclitaxelA ƙasa, bari mu kalli yadda ake yin paclitaxel Semi-synthetic.

Tunda ana fitar da paclitaxel na dabi'a daga Taxus chinensis tare da 'yan tushe, kuma yanayin girma na Taxus chinensis na halitta yana da tsayi, kusan 13.6kg haushi kawai zai iya fitar da 1g na paclitaxel, kuma yana ɗaukar bishiyar haraji 3 zuwa 12 tare da tarihin fiye da shekaru 100. don kula da ciwon daji na ovarian, ƙarancin wadata na dogon lokaci da farashi mai yawa yana sa fasahar haɗin gwiwar wucin gadi na paclitaxel ta haɓaka cikin sauri.

A matsayin wani sinadari da ake hakowa daga tsirrai na halitta, paclitaxel yana da tsari mai sarkakiya.Duk da haka, don magance karancin albarkatun kasa, masanan kimiyya daga sassan duniya suna nazarin hadewar paclitaxel. Har sai da wani masanin kimiya na kasar Faransa ya raba wani abu mai suna.10-DABdaga ganyen British Taxus chinensis, tsarinsa yayi kama da na paclitaxel, kuma abinda ke cikinsa yana da yawa. Ganyen sun fi sake haɓakawa fiye da haushi da rassan, kuma basu da lahani ga Taxus chinensis.

Ta hanyar unremitting kokarin masana kimiyya, da hanyarSemi-synthetic paclitaxelDaga karshe an samar da shi, kuma ba lallai ba ne a yanke Taxus chinensis don fitar da shi. Bayan haka, ta hanyar nazarin tsarin paclitaxel, an samar da wasu magungunan sinadarai irin su docetaxel da albumin paclitaxel, suna kawo karin magungunan warkewa ga masu ciwon daji.

Bayani: Yiwuwar inganci da aikace-aikacen da aka ambata a cikin wannan labarin duk sun fito ne daga wallafe-wallafen jama'a.

Extended karatu:Hande Bio-tech ne yafi tsunduma a cikin hakar da kuma bunkasa haraji. Its core kayayyakin su ne na halitta paclitaxel,10-DAB Semi-synthetic paclitaxel,10-DABIII,docetaxel,cabataxel,da dai sauransu.Idan kana bukatar ka sani game da paclitaxel. APIs na tushen, da fatan za a iya tuntuɓar mu.