Bayanan Samfura
Artemisinin magani ne da ke da tasiri mafi kyau wajen maganin zazzabin cizon sauro.Lactone sesquiterpene ne tare da rukunin peroxide wanda aka samo daga Artemisia annua.Yana da halaye na babban inganci, tasiri mai sauri, kawar da zafi da kuma kawar da zafi na rani, rage rashi zafi, kashe protozoa da ƙananan guba.A halin yanzu, tasirin maganin artemisinin na haɗin gwiwa (ACT) don maganin zazzabin cizon sauro ya kai fiye da 90% a duk faɗin duniya.An yi amfani da shi sosai wajen maganin zazzabin cizon sauro a duk duniya.
1. Aiki
1. Anti malaria
Zazzabin cizon sauro (wanda aka fi sani da ciwon sanyi da zazzabi) cuta ce mai yaduwa da kwari.Cuta ce mai yaduwa ta hanyar cizon jikin dan Adam da Plasmodium ya kamu da shi.Yana iya bayyana hepatosplenomegaly da anemia bayan maimaita harin na dogon lokaci.Artemisinin ya ba da gudummawa ga maganin zazzabin cizon sauro zuwa wani matsayi.Haɗin peroxide a cikin tsarin artemisinin yana oxidizing kuma ƙungiya ce mai mahimmanci don juriya na cizon sauro.Hanyar aiki ita ce ƙungiyar kyauta ta artemisinin a cikin vivo tana ɗaure da furotin na Plasmodium falciparum kuma yana canza tsarin membrane na tantanin halitta na Plasmodium falciparum.Bayan radicals na free radicals sun haɗu da furotin na Plasmodium, membrane bilayer na mitochondria zai kumbura ya tsage, kuma a ƙarshe ya fadi, wanda ya haifar da lalata tsarin kwayar halitta da aikin Plasmodium, kuma chromatin da ke cikin tsakiya zai shafi wasu. girman.
2. Antitumor
Muguwar ciwace ita ce kisa ta farko da ke yin illa ga lafiyar ɗan adam.Idan ba a kula da shi cikin lokaci ba, zai haifar da lafiyar rayuwa.Gwaje-gwajen in vitro sun nuna cewa wani nau'in artemisinin zai iya haifar da apoptosis na nau'ikan kwayoyin cutar kansa, irin su hepatoma, kwayoyin cutar kansar nono, kwayoyin cutar kansar mahaifa da sauransu, kuma yana hana ci gaban kwayoyin cutar kansa sosai.An gano cewa artemisinin zai iya daidaita maganganun cyclin a cikin ƙwayoyin ƙwayar cuta, haɓaka tasirin CKI kuma ya haifar da kama ƙwayar ƙwayar cuta;Ko kai ga apoptosis da hana ƙwayar cutar angiogenesis don tsayayya da abin da ya faru da ci gaban ƙwayar cuta.Ana amfani da Artemisinin don magance cutar sankarar bargo ta hanyar yin aiki da membrane na sel na cutar sankarar bargo, yana haɓaka haɓakar membrane da canza yanayin osmotic, yana haifar da haɓakar ƙwayar calcium a cikin sel, don kunna calpain, yana sa membrane tanta ta kumbura. da fasa, hanzarta sakin abubuwan apoptotic da haɓaka saurin apoptosis.
3. Maganin hawan jini na huhu
Hawan jini na huhu (PAH) yanayi ne na pathophysiological halin da ke tattare da gyaran jijiyar huhu da hauhawar matsa lamba na huhu zuwa wani iyaka.Yana iya zama rikitarwa ko ciwo.Ana amfani da Artemisinin don magance hauhawar jini na huhu: yana iya rage karfin jini na huhu da kuma inganta bayyanar cututtuka a cikin marasa lafiya tare da PAH ta hanyar shakatawa tasoshin jini.Zaiman et al.An gano cewa artemisinin yana da tasirin anti-mai kumburi.Artemisinin da ainihin abubuwansa na iya hana nau'ikan abubuwan da ke haifar da kumburi, kuma suna iya hana samar da nitric oxide ta masu shiga tsakani;Artemisinin yana da tasirin immunomodulatory;Feng Yibai da sauransu sun gano cewa artemisinin na iya hana yaduwar kwayoyin halitta na jijiyoyi da ƙwayoyin tsoka mai santsi, sannan kuma suna taka muhimmiyar rawa wajen kula da PAH;Artemisinin na iya hana ayyukan matrix metalloproteinases, don haka hana gyare-gyaren jijiyoyi na huhu;Artemisinin na iya hana maganganun cytokines masu alaƙa da PAH kuma ya ƙara haɓaka tasirin gyaran jijiyoyi na artemisinin.
4. Tsarin rigakafi
An gano cewa adadin artemisinin da abubuwan da suka samo asali na iya hana T lymphocyte mitogen da kuma haifar da yaduwar ƙwayoyin lymphocytes na linzamin kwamfuta ba tare da cytotoxicity ba.Wannan binciken yana da ƙima mai kyau don maganin T lymphocyte mediated autoimmune cututtuka.Artemisia annua gilashin vinegar na iya haɓaka rigakafin da ba ta dace ba kuma yana haɓaka jimillar abubuwan da suka dace na maganin linzamin kwamfuta.Dihydroartemisinin na iya hana yaduwar B lymphocytes kai tsaye, rage fitar da autoantibodies ta B lymphocytes, rage martanin rigakafi na humoral, hana rigakafi da kuma rage samuwar hadaddun garkuwar jiki.
5. Antifungal
Sakamakon antifungal na artemisinin kuma yana sa artemisinin ya nuna wasu ayyukan ƙwayoyin cuta.Binciken ya tabbatar da cewa ragowar foda da decoction na ruwa na artemisinin yana da tasirin maganin rigakafi mai karfi akan anthrax, Staphylococcus epidermidis, catarrhalis da diphtheria, kuma yana da wasu kwayoyin cutar antibacterial akan tarin fuka, Pseudomonas aeruginosa, Staphylococcus aureus da dysentery bacilli.
2. Filin aikace-aikace
Ana amfani da Artemisia annua azaman maganin zazzabin cizon sauro.Aikace-aikacensa na asibiti ya tabbatar da cewa artemisinin da abubuwan da suka samo asali suna da tasiri na musamman akan Plasmodium falciparum da Plasmodium falciparum, musamman Artemisia annua a, wanda ke da tasiri mai karfi fiye da sauran magungunan artemisinin akan kashe clones na ciki na Plasmodium falciparum.
Sigar Samfura
| BAYANIN KAMFANI | |
| Sunan samfur | Artemisinin |
| CAS | 63968-64-9 |
| Tsarin sinadarai | Saukewa: C15H22O5 |
| Brand | Hkuma |
| Mmaƙera | Yunnan Hande Bio-Tech Co., Ltd. |
| Czance | Kunming,China |
| An kafa | 1993 |
| BBAYANIN ASIC | |
| Makamantu | 3,12-epoxy-12h-pyranol (4,3-j) -1,2-benzodioxepin-10 (3h) -daya, octahydro-3,6,9-tri;artemisiaannual., cirewa;huanghuahaosu;octahydro-3,6,9-trimethyl-3,12-epoxy-12h-pyrano(4,3-j)-1,2-benzodioxepin-10(;qinghausau;qinghausu; QHS; ARTEMISININ 99% |
| Tsarin |  |
| Nauyi | 282.34 |
| HS Code | N/A |
| inganciSpecification | Ƙayyadaddun Kamfanin |
| Ctakardun shaida | N/A |
| Assay | Musamman bisa ga bukatun abokin ciniki |
| Bayyanar | crystal acicular mara launi |
| Hanyar Hakar | Artemisia shekara |
| Iyawar Shekara-shekara | Musamman bisa ga bukatun abokin ciniki |
| Kunshin | Musamman bisa ga bukatun abokin ciniki |
| Hanyar Gwaji | N/A |
| Dabaru | Da yawasufuris |
| PaymentTerms | T/T, D/P, D/A |
| Oa can | Karɓar binciken abokin ciniki koyaushe;Taimakawa abokan ciniki da rajista na tsari. |
Bayanin samfurin Hande
1.All kayayyakin sayar da kamfanin ne Semi-ƙare raw kayan.Abubuwan da aka fi amfani da su ga masana'antun da ke da cancantar samarwa, kuma albarkatun ƙasa ba samfuran ƙarshe ba ne.
2. Abubuwan da za a iya amfani da su da kuma aikace-aikacen da ke cikin gabatarwar duk sun fito ne daga wallafe-wallafen da aka buga.Mutane ba sa ba da shawarar amfani da su kai tsaye, kuma an ƙi sayayya ɗaya.
3. Hotuna da bayanin samfur akan wannan gidan yanar gizon don tunani ne kawai, kuma ainihin samfurin zai yi nasara.
